Colon cancer and gut microbiota 


Although genes contribute to colorectal cancer, the gut microbiota are also an important player. As well, their role after a diagnosis of colon cancer may play an even more crucial part in the  successful outcome of cancer treatments.

Cancer treatments

One of the key areas for patients being treated for colorectal cancers is the disturbance to gut microbiomes, particularly from standard oral cancer medications including targeted treatments which are necessary to treat and kill cancer cells, but also come at a cost; impacting, numbers and functionality of gut microbiota. This can exacerbate symptoms and progression of cancer cells. Evidence is increasing that the intestinal microbiota composition affects tumour evolution of various origins far beyond the intestine. This is exciting and reflects likely a complex interaction of various members of this highly complex bacterial world with various immune pathways.

Try LACTIS or sister product CHITSU – Safe, reliable, convenient – food for your own microbiota. No live bacteria! Not a probiotic.

The role of diet and microbiota

Sometimes as a result of  your previous diet then the addition of colon cancer treatments; some species of your gut’s bacteria can even become extinct, leading to further health problems; severely compromising wellbeing and  your survivorship. Our diets certainly influence the composition of our microbiota although importantly, long-term dietary patterns outweigh short-term changes in diet. It is not surprising that a particular diet selects for certain microbiota at the expense of others.

 

Gut microbiota, inflammation and colorectal cancer

A study published on Science Direct provides some fascinating knowledge about the relationship between Gut microbiota, inflammation and colorectal cancer…. the study reports that: “accumulating evidence suggests that chronic infection and the ensuing inflammation contributes to tumour initiation and tumour progression.

Prevention of colon cancer

Based on current understandings of the roles of microbiota in colon and GI cancer in general, targeting the gut microbiota is a promising avenue in order to prevent cancer or at least stop the increase of cancerous cells”. There is still a lot of scope for extended research in the area of cause, effect and treatment roles for cancer patients. Even though research is in progress, it seems clear that by improving gut microbiota by way of diet and by establishing or re-establishing healthy populations of gut bacteria; prevention of colon cancer may be a reality in the near future.

Try LACTIS or sister product CHITSU – Safe, reliable, convenient – food for your own microbiota. No live bacteria! Not a probiotic.

Solutions to Side Effects of Colon Cancer Treatments

We know that just the simple addition of the right amount of fibre from different types of fruits, vegetables and cereals can improve numbers, function and types of gut microbiota.

However, once you have a diagnosis of colon cancer and especially if you have begun treatment, it is certainly not advisable to dramatically increase your fibre intake when taking conventional treatments. It is also not in advised to consume large amounts for fermented foods at this time as often this rapid change will create more gas, inflammation, pain and discomfort.

Many patients experience side effects such as diarrhea, bloating and pain from oral colon cancer treatments. Depending upon the treatments used; intravenous chemotherapies can also further impact an already compromised gut. LACTIS and CHITSU provide food for your own gut bacteria to flourish. A simple and effective solution; LACTIS or CHITSU can be safely consumed whilst undergoing colon cancer treatments.

Surgical gut rearrangements as a result of colon cancer

Colon cancer treatments become even more problematic with the added complication of surgery, when various lengths of colon may be removed and re-joined or diverted into ostomy bags with an outlet on the surface of the skin and a stoma created – these are called colostomies or ileostomies depending upon location. Sometimes these surgical diversions are temporary and sometimes permanent.

This presents a very special set circumstances for dietary help, adaptation and adjustment advice as well as help with gut microbiota. If this describes your situation; I suggest you contact me, Grace Gawler for  personalised assistance

Solutions

For some patients, treatment with probiotics has been deemed useful; however, oncologist and researchers are now commenting that “live bacteria probiotic supplements” can be problematic for some patients. Some studies have indicated that not enough probiotic gets to where it is needed, while others have found that the probiotic supplements passes through.

Try LACTIS or sister product CHITSU – Safe, reliable, convenient – food for your own microbiota. No live bacteria! Not a probiotic.

Weight loss during cancer treatment

Compromised gut barrier function because of dysbiosis or intestinal inflammation can lead to translocation of microbial substances and the development of systemic inflammation with potential consequences for patients prone to cachexia. (Cachexia is weakness and wasting of the body due to severe chronic illness).

A recent study showed that non digestible oligosaccharides (NDOs- NDO’s resist hydrolysis and digestion in the human digestive system and are partially or completely fermented by the colonic microbiota in the large intestine) modulate the gut microbiota may constitute a new nutritional strategy to modulate gut microbiota with positive consequences on cancer progression and associated cachexia. However care must be taken in terms of quantity of NDO’s if you have previously had a low fibre diet. The addition of a biogenic lactobacillus ferment LACTIS or CHITSU, along with a graduated increase in NDO’s can assist with offsetting issues associated with cachexia. 

Efforts to preserve the integrity of the gut epithelial barrier and/or limit intestinal inflammation in cancer patients may help avoid the serious metabolic alterations associated with cachexia.

Based on current understandings of the roles of microbiota in gastro intestinal and colo-rectal cancer, targeting the gut microbiota is a most promising avenue in order to prevent cancer or at least stop the increase of cancerous cells.

Therefore there is a role for consuming safe, biogenically produced LACTIS or CHITSU – lactobacillus ferment as an addition to conventional colon cancer treatments.

Metabolic syndrome is increasingly associated with cancer development and resulting mortality. Insulin resistance is the linchpin in the development of metabolic syndrome and has been observed in many different forms of cancer such, as prostate, breast, and colorectal cancers. Research has linked  metabolic syndrome with regular use of all artifical sweeteners, impcating gut microbiota!

Gut microbiota can regulate various metabolic features, such as nutrient harvesting, liver metabolism of lipids and cholesterol and fat storage, and can also compromise the intestinal mucus barrier when diets low in dietary fiber are introduced.

Try a  LACTIS starter pack today – 15x 10 ml sachets and notice the difference!

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Prevention, Management, Wellbeing and Survivorship.